Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp376 | Other diseases of bone and mineral metabolism | ECTS2014

Blocking β-adrenergic signaling attenuates calorie alteration- induced bone marrow adiposity

Baek Kyunghwa , Hwang Hyorin , Park Hyung-jung , Baek Jeong-hwa

We sought to elucidate the effects of dietary caloric alterations on bone marrow adiposity and the effects of β-adrenergic signaling on marrow stromal cells’ adipogenic differentiation. Male 6-week-old C57BL/6 mice were assigned into three groups: an ad-libitum fed control diet (CON; 10 kcal% fat), a high calorie diet (HIGH; 60 kcal% fat) and a low calorie diet (LOW; 30% kcal restriction vs CON diet). In each diet group, mice were treated with vehicle (VEH: ...